By William B. Coleman - Molecular Diagnostics: For the by Gregory J. Tsongalis (Editor) William B. Coleman (Editor)

By Gregory J. Tsongalis (Editor) William B. Coleman (Editor)

ISBN: 1588293564 making the most of the various significant advances that experience happened on the grounds that their groundbreaking first variation used to be released, William B. Coleman and Gregory J. Tsongalis have up to date and multiplied their hugely praised educational consultant to molecular diagnostic concepts to incorporate not just superior conventional equipment, but in addition absolutely new molecular applied sciences, a few now not but in regimen use. The authors supply state-of-the-art molecular diagnostics for genetic sickness, human cancers, infectious ailments, and id trying out, in addition to new insights into the query of caliber insurance within the molecular diagnostics laboratory. extra chapters tackle different applied sciences present in the medical laboratory which are complementary to molecular diagnostic methodologies, and in addition talk about genetic counseling and the moral and social matters concerned with nucleic acid checking out.

Authoritative and state of the art, Molecular Diagnostics: For the scientific Laboratorian, second variation is the basic textbook of selection for a person operating in molecular diagnostics and who desires to stay present with this quickly altering box.

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Extra resources for By William B. Coleman - Molecular Diagnostics: For the Clinical Laboratorian: 2nd (second) Edition

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Andreas Vesalius, who is credited as the founder of modern anatomy, was such an individual. He was the first to do extensive dissections and accurately document the anatomical information in text and illustration (4). The importance of this lies in the transition from animal to human dissections. Accurate anatomical data would become available and true progress in the other anatomical sciences, histology and zoology, could take place (4). Another individual of this type was Giovanni Battista Morgagni, a successor to Vesalius, who combined anatomic dissection with clinical history to describe pathologic anatomy (4).

It can be surmised that the purpose was to enhance those traits that were considered desirable. Between the 6th and 4th centuries BCE, the Greeks discussed inherited traits and the relative influence of inheritance versus the environment with respect to birth defects (13). Arguments were put forth as to how humans developed and what was the source of the traits that were easily recognized between parent and offspring. Progress was slow until Maupertius described the first inherited genetic disorder through four generations of a family in 1752 (13).

In turn, RNA molecules serve as blueprints for the ordering of amino acids by ribosomes during protein synthesis or translation. This simple representation of the complex interactions and interrelationships among DNA, RNA, and protein was proposed and commonly accepted shortly after the discovery of the structure of DNA. Nonetheless, this paradigm still holds more than 45 years later and continues to represent a guiding principle for molecular biologists involved in all areas of basic biological, biomedical, and genetic research.

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