By K. Lassoued, D. Ghez (auth.), Guy Touchard, Pierre Aucouturier, Olivier Hermine, Pierre Ronco (eds.)
The kidney involvement in monoclonal gammopathies is an engaging box of study and of serious hindrance to scientific perform. The publication is split into 4 components.
The first one is dedicated to "the culprits" and comprises contributions from best investigators in B-cell proliferations, immunoglobulin synthesis, secretion and constitution, mild chain uptake and metabolism within the kidney.
The moment and 3rd components are dedicated to "the victims": the tubule and the glomerulus. New insights into pathophysiology, medical and histological good points, therapy of renal lesions and remedy of B-cell proliferations are mentioned in myeloma solid nephropathy, Fanconi's syndrome, Randall-type monoclonal immunoglobulin deposition ailment and non amyloid prepared monoclonal immunoglobulin deposits. within the final half, immunoglobulinic amyloidosis is taken into account with a around desk dedicated to stem phone transplantation and new promising cures in AL amyloidosis.